In today's topic we are going yo see about "CELLS IN CONNECTIVE TISSUE". Tissues are classified into 4 types . last topic we discussed about epithelial tissue and in today's topic we are going to see about connective tissue. Connective tissue has so many wide varieties of cells such as macrophages, adipocytes, mast cells, reticulin fibers etc...it's a vast topic so we'll discuss about the types of connective tissue in our next blog.
I have done video of these slides in both English and Tamil. You can get the detailed explanation of these slides. If you and queries or suggestions kindly post in the comments section below.
Channel link:
https://www.youtube.com/channel/UCZrabu-CtMa5AEexu1j2GNw
English video:https://youtu.be/rcX3w6WIrOs
Tamil video: https://youtu.be/7AgP4VJsvG4
TYPES OF TISSUES:
There are 4 main types of tissues each with subtypes .they are
1.EPITHELIAL TISSUE OR
EPITHELIUM.
2.CONNECTIVE TISSUE.
3.MUSCLE TISSUE.
4.NERVOUS TISSUE.
2. CONNECTIVE TISSUE:
Connective tissue is the most abundant tissue in the body.
The connective tissue cells are more widely separated from each other than in epithelial tissues , and the intercellular substance (matrix) is present in considerably larger amounts.
There are usually fibers present in matrix, which may be semisolid jelly like consistency or dense and rigid ,depending upon the position and function of the tissue.
The fibers form a supporting network for the cells to attach to.
CELLS IN CONNECTIVE TISSUE:
Most types of connective tissue have a good supply.
Major functions of connective tissue are:
binding and structural support , protection , transport , insulation.
The cells in connecting tissue are
FIBROBLASTS
FAT CELLS (ADIPOCYTES)
MACROPHAGES
LEUKOCYTE
MAST CELLS.
FIBROBLASTS:
They are larger cells.
They manufacture collagen, elastic fiber and a matrix .
Very fine collagen fibers called as reticulin fibers are found in highly active tissue such as liver.
Fibroblasts are highly active in tissue repair (wound healing) where they may bind together the cut surface of wound or form the granulation tissue following tissue destruction.
The collagen fibers formed during the wound healing shrink as they age .
FAT CELLS (ADIPOCYTES):
These cells occurs singly or in groups in many types of connective tissue and are especially abundant in adipose tissue.
They vary in size and shape according to the amount of fat they contain.
MACROPHAGES:
They are large irregular shaped cells.
Some are attached to the connective tissue fibers and others are motile.
They are important for body’s defense mechanism because they are actively phagocytic , engulfing and digesting cell debris ,bacteria and other foreign bodies.
Their activities are typical of the monocyte –macrophage defense mechanism.
LEUKOCYTES:
White blood cells are found in small numbers in healthy connective tissue but neutrophils migrate in significant numbers during infection when they play an important part in tissue defense .
Plasma cells develops from B-lymphocytes ,a type of WBC.
They synthesize and secrete specific defense antibodies into blood and tissue.
MAST CELLS:
Mast cells are found in loose connective tissue under fibrous capsule of some organs (eg: liver ,spleen).
Their cytoplasm is packed with granules containing heparin ,histamine and other substances , which are released when the cell is damaged by any disease or injury.
The release of granular content is called degranulation.
Histamine is involved in local and general inflammatory reactions , it stimulates the gastric juice an is associated with the development of allergies and hypersensitivity states.
Heparin prevents the coagulation of blood and it helps to maintain blood flow through the inflamed tissues , supplying cells with oxygen and glucose and bringing additional protective leukocytes to the area.
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